నైరూప్య

Effect of pregnancy on packed cell volume and hemoglobin level among sudanese pregnant women attending antenatal care at omdurman military hospital (khartoum state)

Mohamed Abdalla Shareef Ahmed, Ibrahim A Ali, Omer A Musa

Introduction: During pregnancy women undergo several structural and physiological changes almost in most body systems including the hematological profile. The main reported hematological change is plasma expansion and hemodilution which affect the red blood cells (RBCs) and hemoglobin (Hb) and other indices including packed cell volume (PCV). Objectives: The objectives of this study were to assess the effect of pregnancy on PCV and Hb among Sudanese pregnant women and derive a formula for the normal values in pregnant women in relation to the packed cell volume. Methods: An analytical case control study was conducted in Khartoum state, Sudan 2017. The study included 10 Sudanese pregnant women not taking tonics, 20 Sudanese pregnant women taking tonics attending antenatal care at Omdurman Military hospital and 20 Sudanese nonpregnant women in the same age group as control. A questionnaire was used to collect sociodemographic and clinical data. Blood sample was collected and Complete blood count (CBC) was measured by using automated cell counter Sysmex. Results: The study population comprised 50 women, 10 pregnant women not taking tonics, 20 pregnant women taking tonics and 20 non-pregnant women as control; The results showed a non-significant statistically decrease in PCV in women not taking tonic (0.220) when compared to pregnant taking tonics and non-pregnant. There was also non-significant statistically decrease in Hb in pregnant women not taking tonic compared to pregnant taking tonics and non-pregnant with P values (0.104). Conclusion: During pregnancy there was statistically decrease in PCV values, and count and by considering the hemodilution factor there was a significant increase in values in pregnant ladies not taking tonics.