జర్నల్ ఆఫ్ కార్డియోవాస్కులర్ మెడిసిన్ అండ్ థెరప్యూటిక్స్

నైరూప్య

Hypertension Risks from the Iron Brake Particulate Matters

William J Rowe

 Of 12 moonwalkers, James Irwin on the day after return from Apollo 15 mission, showed extraordinary bicycle (B) stress          test (ST) hypertension (275/125) after 3 minutes exercise; supervising > 5000 maximum treadmill  ST,  author  never  witnessed ST- blood pressure approaching this level. Symptom-limited maximum B stress test showed “cyanotic fingernails, possibly venous blood trapped peripherally, supporting author’s “Apollo  15  Space  Syndrome,”  postulating  that  severe  fingertip pain during space walks, triggered by plasma fluid, trapped distally; mechanism could be related to endothelial dysfunction, providing “silent ischemia” warning. Neil Armstrong returned to Earth with severe  diastolic  hypertension  (160/135), consistent with ischemic left ventricular dysfunction; 50 mm increase in comparison with resting BP 110/85. With inhalation of lunar dust, brought into habitat on space suit, with high lunar iron (I) this dust inhalation, along with reduced (R) space flight- transferrin, R antioxidant, calcium (Ca) blocker-magnesium, conducive to severe oxidative stress, Ca overload     with potential endothelial injuries. Using moonwalker studies as example, my recent editorials show that I dust, released from brakes, with over 90% of brakes made of I, is a major hypertension factor and may also contribute to myocardial infarctions.