నైరూప్య

In-hospital outcomes of patients undergoing manual thrombus aspiration in primary PCI for acute STEMI with high thrombus burden.

Nguyen Thuong Nghia, Nguyen Tuan Anh, Nguyen Thi Anh Nga, Nguyen Thuong Le

Background: Routine thrombus aspiration during primary PCI does not improve clinical outcomes. However, the outcomes of manual thrombus aspiration for patients undergoing primary PCI for acute STEMI with high thrombus burden are still unclear.

Objective: Evaluate the in-hospital outcomes of using manual thrombus aspiration in STEMI patients undergoing primary PCI and showing a high thrombus burden.

Methods: Intervention prospective study.

Results: 147 STEMI patients with high thrombus burden in coronary angiography divides into thrombus aspiration and PCI (n=71) or conventional PCI (n=76). The ST-segment resolution and TIMI myocardial perfusion grading (TMP=3) were significantly higher in the aspiration+PCI group compared with the conventional PCI group. The in-hospital mortality rate was lower in the aspiration+PCI group compared with the conventional PCI group (10.5% versus 1.4%; P=0.034). There were no significant differences in the incidence of stroke between the two groups.

Conclusion: In STEMI patients with high thrombus burden, manual thrombus aspiration improved inhospital mortality, ST-segment resolution, and TIMI myocardial perfusion grading.